MED REVIEW MONDAY Vancomycin is an antibiotic that is used to treat gram-positive infections. It works by inhibiting cell wall synthesis in bacteria. It is used prophylactically during surgery, if a MRSA or C. dif infection is suspected, and commonly with catheter infections. It is mainly given through IV. The drug can cause pain and thrombophlebitis during administration so it is given very slowly (10 mg/min) and ideally through a central line, PICC or infusion port. One side effect that is essential to know is red man syndrome: a rash that can occur on the face, neck and upper torso of a patient receiving Vanco - as seen in this picture. For this reason, the med is almost always ordered with an antihistamine such as Benadryl.
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