Monday, January 23, 2012
MED REVIEW MONDAY Penicillin is a very popular antimicrobial which works by interfering with the synthesis of bacteria cell walls. It was first made available to the public in the early 1940’s and was sort of a “silver bullet” drug - it worked on most gram positive infections. Unfortunately, there can be severe side effects, ranging from a rash or GI upset to a full anaphylactic reaction. Over 10% of the population is allergic to the drug! Penicillin has been used so widely for the past seven decades that many bacteria have developed resistance, so scientists went right on ahead and started producing combination therapies that included resistance inhibitors in the same dosage (haha, evolution - take that!) NCLEX tip: Penicillin should be taken on an empty stomach (one hour before meals or two hours after) because it is destroyed by gastric acid. 

MED REVIEW MONDAY

Penicillin is a very popular antimicrobial which works by interfering with the synthesis of bacteria cell walls. It was first made available to the public in the early 1940’s and was sort of a “silver bullet” drug - it worked on most gram positive infections. Unfortunately, there can be severe side effects, ranging from a rash or GI upset to a full anaphylactic reaction. Over 10% of the population is allergic to the drug! Penicillin has been used so widely for the past seven decades that many bacteria have developed resistance, so scientists went right on ahead and started producing combination therapies that included resistance inhibitors in the same dosage (haha, evolution - take that!) NCLEX tip: Penicillin should be taken on an empty stomach (one hour before meals or two hours after) because it is destroyed by gastric acid. 

Posted at 7:35 PM 22 notes Tags: penicillin nursing pharmacology nclex patient education history of medicine antibiotics microbiology

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